Mass Directed Flash Purification System Confirms Compounds in Less Steps

Biotage has launched the Isolera Dalton, a fully automated, miniaturised mass directed flash purification system. According to the company, the new system raises the bar for flash purification by integrating a miniaturised mass detector and an advanced flash chromatography system into one commercially available platform.

The mass detector and Isolera Spektra flash purification system are seamlessly integrated via the Isolera Dalton Nanolink unit, an intelligent sampling device that handles all fluids and synching calculations between the two units. Isolera Dalton easily fits inside a standard fume hood, requires no external pumps and is capable of both normal and reverse-phase separations, so it is completely compatible with the diverse purification needs of the modern research laboratory.

Dr. Sunil Rana, Global Product Manager, Biotage, said: “Compounds are identified in real time during purification and this informs the flash fractionation process, enabling the correct product to be collected by the system. The system automatically accommodates different column sizes and flow rates, overcoming major issues with simple splitter-based systems. Isolera Dalton significantly reduces the number of steps required to purify and confirm a target compound, thus improving workflow and increasing confidence that chemists have synthesised what was intended. Quite frankly, there is nothing else like it on the market today, or that even comes close.”

The instrument uses a wizard-based approach to method development; simple on screen prompts guide chemists through the system, even those whose expertise or priorities lie in compound synthesis rather than analysis.

Biotage AB, Sweden, +46 18 56 57 10, info@biotage.com, www.biotage.com.