Granulation and Drying Process Eliminates Operator Contact

The ROTO CUBE is a high shear granulator and single pot processor for the complete wet granulation and drying process of any type of product, from the loading of raw materials to the discharge of dry granules. The process is carried out in a single, contained bowl, thus reducing risk of contamination and increasing protection for the operators. Therefore, the Roto Cube is highly recommended for manufacturing high potency drugs.

The ROTO CUBE design allows for the optimisation of room layout. The product bowl is located in the processing area, hinged to a column, and installed through the wall. Utilities can be located in a technical area, minimising the process area.

ROTO CUBE can be equipped with a lifting system to adjust the height according to the task; during the process, as well as maintenance and inspection, the machine can be lowered to facilitate access to the bowl. In addition, the bowl can be positioned in a higher position for a good product flow into a collecting intermediate bulk container (IBC) during discharge.

The product bowl can tilt during the vacuum drying phase to provide gentle treatment of granules, preserving them from breakage. Moreover, the gas stripping system (GA.ST.), by injecting an inert gas through the product mass, enhances evaporation rate. Microwave assisted drying is also available.

The machine guarantees reliable monitoring and control of all the process parameters, including accurate detection of the process end-point.

The ROTO CUBE CIP system, with self-cleaning metallic filters, is very quick and easy to validate.

A complete range of machines for laboratory and production purposes, up to 3,000 l (bowl capacity), are available.

IMA S.p.A., IMA Active division, +39 051 6514111, mktg.soliddose@ima.it,

www.ima-pharma.com.

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