MGI launches high-throughput sequencing kit at genome conference
At the 17th International Conference of Genomics (ICG-17) on 7-9 September in Riga, Latvia, MGI introduced its new commercial sequencing chemistry HotMPS and together with BGI STOmics, a spatial transcriptomics grant program.
Key highlights:
- At ICG-17, MGI introduced its commercial sequencing chemistry HotMPS and together with BGI STOmics, a spatial transcriptomics grant program.
- The sequencing kit uses MGC's DNBSEQ technology to maximise powerful data output capacity and effectively saves material costs.
- The technology provides a research base for advanced analysis of gene expression, cell type identification and cell-to-cell communication in nascent tissue microenvironment.
MGI Tech, in collaboration with BGI Genomics, BGI Research and the Latvian Biomedical Research and Study Centre, brought the 17th International Conference of Genomics (ICG-17) to Europe this year on 7-9 September in Riga, Latvia.
Under the theme OMICS FOR ALL, ICG-17 aims to provide a platform where leaders in the emerging field of genomics meet and share their experience, knowledge, and insights, to advance understanding and collaborations in omics. This year’s conference was held in Riga, a trade, transit, and industrial center in Latvia, as well as home to MGI’s Latvian facility, which since 2019 has been a dynamic hub for research and development, production, logistics and training for its customers and scientific collaborators in Europe and Africa.
ICG-17 provided a comprehensive and insightful scientific agenda filled with presentations and sharing by expert speakers and scientific sessions on topics including single-cell and Stereomics, microbiome and multi-omics, precision medicine, multidisciplinary view on COVID-19 research, women in science, and biobanks and health data in personalised medicine development. The event also saw MGI scientists sharing the data performance of the new HotMPS chemistry on G400 and T7 including results on various applications such as WGS, WES, RNA-seq, and third-party libraries.
HotMPS inherited the advantages of MGI’s proprietary DNBSEQ technology to deliver low error rates, low duplication rates, and low index hopping, while achieving fundamental breakthroughs in the nucleotides and enzymes used in the sequencing process. The high-throughput sequencing kit, which is commercially available in selected countries, was launched to be compatible with DNBSEQ-G400 in late April and has now been further expanded for use on DNBSEQ-T7 which vastly improves speed, throughput, and flexibility.
In his presentation, key speaker Dr. István Szatmári from the University of Debrecen in Hungary showcased the quality of the new chemistry on MGI platform and confirmed the suitability of HotMPS combined with G400 for global transcript profiling.
At the ICG-17 in Riga, BGI STOmics announced a spatial transcriptomics grant program, which will provide 12 Stereo-seq (Spatial Enhanced Resolution Omics-Sequencing) chips (1cm*1cm), sequencing and data analysis to selected projects by researchers across the globe, excluding mainland China. MGI will provide MGI sequencing products for this Grant.
This new spatial temporal technology provides a powerful research base for advanced analysis of gene expression, cell type identification and cell-to-cell communication in nascent tissue microenvironment with its unprecedented field-of-view, high throughput, ultra-high resolution in spatial transcriptomic research.
Based on DNA Nanoball (DNB) technology, Stereo-seq chip is designed for in situ mRNA capture and localisation. Subsequently captured mRNAs can be restored to their spatial positions by establishing the mapping relationship between spatial coordinates ID (CID) and chip's coordinate positions, while spatially resolved molecular information can also be obtained using Stereo-seq.
“I am thrilled that so many brilliant minds from Europe, Africa and beyond are gathering to share their knowledge and experience in further advancing genomics science,” said Dr. Yong Hou, general manager of MGI Europe and Africa.
“With the mission to develop and promote advanced life science tools for future healthcare, we at MGI are proud to introduce our latest innovations. DNBSEQ-T7 boasts high data quality and flexible operation mode. Its high degree of automation maximises T7’s powerful data output capacity and effectively saves manpower and material costs.
"It fully supports genome-wide sequencing, ultra-high-depth whole exome sequencing, epigenome sequencing, tumor large gene detection, and other application scenarios with its high speed, high flexibility, and ultra-high throughput advantages. In addition, we are excited to facilitate scientific discoveries through fruitful discussions at ICG-17, while empowering scientists with our new Stereo-seq grant.”
Since 2006, ICG has brought together over 1,000 top scientists, practitioners, institutional executives, Nobel Laureates, academics, and entrepreneurs from around the world for open sharing and discussion related to OMICS. There have been more than 10,000 on-site attendees and 10 million from online in the past 17 years.
"Bringing brilliant minds together is always a good idea. I am excited to meet everyone during ICG-17,” said Prof. Fred Dubee of BGI and key founder of ICG.