RSSL expands capabilities in particle characterisation
RSSL’s physical chemistry department has revealed an expansion of its particle characterisation capabilities, which includes new equipment to measure the surface area of powder particles.
Surface area measurements are important in the determination of the performance of excipients and APIs and for some of the most commonly used excipients is a regulatory requirement.
The new gas sorption instrument, Micromeritics TriStar II 3020, is used for the measurement of specific surface area (SSA) and total pore volume. SSA is linked with solubility (dissolution), rate of moisture sorption and overall chemical reactivity of pharmaceutical APIs and excipients, and can be relevant to patent claims. With this new equipment RSSL reports that it will be able to determine SSA from as low as 0.001 m2/g using krypton gas.
RSSL provides analytical, investigational, consultancy and training services to clients in the pharmaceutical, biopharmaceutical and healthcare sectors.