ProBioGen
Another global pharmaceutical company has licensed ProBioGen’s GlymaxX ADCC-enhancement technology. The license covers the modification of the pharmaceutical company's antibody production platform for the generation of antibodies with enhanced potency. The continued licensing success demonstrates the industry’s endorsement of GlymaxX.
The GlymaxX technology is highly versatile since it can be applied to any starter or production cell line. It allows both the robust, permanent modification of established antibody expression platforms as well as the rapid conversion of existing antibody producer clones to produce ADCC-enhanced molecules.
The GlymaxX technology is based on the stable expression of a heterologous enzyme in the antibody producing cells. GlymaxX prevents antibody fucosylation almost completely but moreover allows the exact adjustment of any desired fucosylation level through the controlled addition of fucose into the culture medium.
The license with an option for a commercial license covers the modification of the company’s antibody production platform and the generation of multiple antibodies with enhanced ADCC potency.
The technology can be licensed royalty-free, based on milestone-dependent license fees only.
ProBioGen AG, +49 30 924 006 0, cmo@probiogen.de, www.probiogen.de / www.glymaxx.de.